Pfam 3.1: 1313 multiple alignments and profile HMMs match the majority of proteins

نویسندگان

  • Alex Bateman
  • Ewan Birney
  • Richard Durbin
  • Sean R. Eddy
  • Robert D. Finn
  • Erik L. L. Sonnhammer
چکیده

Pfam is a collection of multiple alignments and profile hidden Markov models of protein domain families. Release 3.1 is a major update of the Pfam database and contains 1313 families which are available on the World Wide Web in Europe at http://www.sanger.ac.uk/Software/Pfam/ and http://www.cgr.ki.se/Pfam/, and in the US at http://pfam.wustl.edu/. Over 54% of proteins in SWISS-PROT-35 and SP-TrEMBL-5 match a Pfam family. The primary changes of Pfam since release 2.1 are that we now use the more advanced version 2 of the HMMER software, which is more sensitive and provides expectation values for matches, and that it now includes proteins from both SP-TrEMBL and SWISS-PROT.

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عنوان ژورنال:
  • Nucleic acids research

دوره 27 1  شماره 

صفحات  -

تاریخ انتشار 1999